All sporadic cancer is caused by acquired somatic mutations (mutations that take place within cells of the body that are not passed down/inherited). Mutations often occur by incorrect repair of DNA damage by impaired DNA pathways such as the nucleotide excision repair (NER) pathway and the DNA mismatch repair (MMR) pathway.
By Jenni Lacey, Cancer Research UK
At Cancer Research UK, we invest over £350 million each year on high-calibre cancer research which we believe has the potential to provide the greatest benefit to the public and cancer patients. We are always looking for novel ways to spark and fund creative ideas, and encourage fresh thinking. That’s why we’ve developed new ways of supporting research and stimulating innovation. We have funding schemes that are open to researchers from all backgrounds, including biochemists, and those not currently working in cancer research.
By Priya Hari, University of Edinburgh
It’s season 11 of The Big Bang Theory – the well-loved comedy showcasing a group of stereotypical nerds (or as I like to think, scientists who are normal people like me and you). The show, based on the social lives physicists, engineers and biologists, is usually a comedic affair, but episode 2 of season 11 went a little beyond that. It highlighted a number of matters that certainly can be related to by a scientist of any discipline.