The rise and demise of antibiotics

By Rietie Venter, University of South Australia

In the 1940s the well-known British vet James Herriot administered the brand-new antibiotic penicillin to a sick animal and the amazing, speedy recovery that followed was in his words “like witnessing a miracle”. Barely 70 years later, I got an infection in a caesarean wound and I was terrified that these miracle drugs would not work anymore.

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The metabolic benefits of exercise

By Ralitsa Madsen, Institute of Metabolic Science, Cambridge, UK

RalitsaM2Iris, the Greek Goddess messenger between humans on Earth and the Gods on Mount Olympus, has made an entry into human biology by providing inspiration for the name of a skeletal muscle-derived hormone. Irisin belongs to the class of myokines, which are molecules released by skeletal muscle in response to exercise and act as messengers to other tissues, including liver, fat and the brain. Given the beneficial effects of exercise, particularly in the context of obesity and Type 2 Diabetes, major efforts have been invested into discovering myokines of potential therapeutic value. Irisin seems to have it all, with multiple animal studies confirming its metabolic benefits such as lowering of blood glucose and lipid levels. Continue reading “The metabolic benefits of exercise”