Epigenetic tags for personalized diagnoses

By Sarah Kearns, University of Michigan, USA

There’s more to our genetics than what’s within our DNA code. Though the code itself is the basis for life, on its surface there are chemical alterations that change how it’s expressed. Because DNA’s structure is that of a helix, modifications either make it coil up or unwind where the unwound form allows for transcription. Epigenetics is the concept of chemical marks on DNA, or associated proteins that control gene activity, that act independently of the genetic code itself.

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