Most biologists would agree that the most extraordinary development of the 21st century has been the discovery and manipulation of the CRISPR/Cas9 method of gene editing – a natural defence mechanism that bacteria use to defend against viral infection which scientists have hijacked to modify the DNA sequence of living cells. Continue reading Prime editing – a cutting edge new development in genomic engineering
By Anastasia Stefanidou, Communications Officer, Biochemical Society
Gene editing and the use of CRISPR to fix genetic disease in human embryos seem to be all over the news these days.
It has just been reported that a team of American and South Korean scientists have successfully used CRISPR, a tool that cuts DNA with more precision than any other genome editing technology, to fix a genetic defect in human embryos that can cause serious heart problems. Continue reading “An introduction to gene editing”
By James Brown, Education and Public Engagement Manager, Biochemical Society
To Hoover. To Google. To CRISPR. As Jennifer Doudna pointed out at the launch of her new book, A Crack in Creation, once your invention has become a verb, you know you’re onto something big. And CRISPR (or CRISPR-Cas9) is certainly big; it doesn’t seem like hyperbole to describe it as a ‘game-changer’ in molecular bioscience.