By Ralitsa Madsen, Institute of Metabolic Science, Cambridge, UK
Iris, the Greek Goddess messenger between humans on Earth and the Gods on Mount Olympus, has made an entry into human biology by providing inspiration for the name of a skeletal muscle-derived hormone. Irisin belongs to the class of myokines, which are molecules released by skeletal muscle in response to exercise and act as messengers to other tissues, including liver, fat and the brain. Given the beneficial effects of exercise, particularly in the context of obesity and Type 2 Diabetes, major efforts have been invested into discovering myokines of potential therapeutic value. Irisin seems to have it all, with multiple animal studies confirming its metabolic benefits such as lowering of blood glucose and lipid levels. Continue reading “The metabolic benefits of exercise”
By Tilly Potter, Department of Twin Research, King’s College London
I recently began my PhD during which I will be carrying out investigations into the human microbiome – that is, all of the microbes we harbour on and in our bodies and their genetic material. The reasons why I was attracted to this area are likely similar to those of other scientists who have entered this field; microbiome research is still in its relative infancy yet appears to hold enormous potential regarding understanding differences between health and disease, with the number of diseases or adverse health states examined continuing to increase with time. This makes it an incredibly diverse and exciting area to work within! Continue reading “Microbiome manipulation – full steam ahead?”
By James Brown, Education and Public Engagement Officer, Biochemical Society
The dominating spectacle of dinosaurs and dodos seemed to spark the imagination of guests at the British Society for Gene and Cell Therapy’s annual Public Engagement Day, this year held at the Museum of Natural History in Oxford.
Biochemical Society members Evita Hartmane, Heba Ismail and James Tomkins joined me for the first outing of our new public engagement activity: Scientific Scissors. The activity is all about Genome Editing – What is it? How does it work? What can we do with it? What should we do with it? Why is it important? The aim is to start conversations about new technologies and give people the opportunity to ask questions whilst engaging with the ethical issues involved.
Continue reading “Scientific Scissors – The first cut”
By Dr Derry K Mercer, Principal Scientist at Novabiotics Ltd & member of the Biochemical Society Policy Advisory Panel
The UK Government recently published a Green Paper ‘Building our Industrial Strategy’ in which the urgent need for developing skills in further/higher education and the workforce was outlined. The document noted that while the UK higher education system was strong, our achievements in basic and technical skills was relatively poor and has led to the lower levels of productivity compared with other advanced economies.
The skills issues were outlined as follows:
- lack of basic skills;
- shortage of high-skilled technicians below graduate level;
- skills shortages in STEM sectors;
- the need for informed career choices;
- lack of lifelong learning opportunities.
For anyone working in the molecular biosciences, whether in academia or industry, most of these concerns can hardly have come as a surprise and represents a huge problem for a growing sector that currently generates turnover of over £56 billion per annum. Indeed, the skills and productivity gaps were pointed out in an earlier UK government document ‘Fixing the foundations: Creating a more prosperous nation’ in 2015. Continue reading “The demand for skills development in the molecular biosciences”