SARS-CoV 2: eXplaining the differences in death rates

As the SARS-CoV-2, or more commonly known as Covid-19, pandemic continues to spread, epidemiologists seem to be churning out some mindboggling numbers. Recently, I came across a puzzling statistic which concluded that women were less likely to die from contracting Covid-19 than men were. Additionally, this was in the above 65 years category, where there is a higher percentage of women than men. Delving into the literature, looking for an explanation to make sense of the difference in death rate, I found an extremely neat explanation relating to X chromosome inactivation. Continue reading SARS-CoV 2: eXplaining the differences in death rates

Guest editing an issue of ‘Essays in Biochemistry’ on the Extracellular Matrix

The extracellular matrix (ECM) has fascinated me ever since I was a student, newly introduced to the concept that interactions between cells build and sustain multi-cellular tissues. Unlike the cells of plants or fungi, animal cells have no cell wall: molecules secreted by animal cells into the extracellular space can bind directly to plasma membrane receptors to influence gene expression and cell behaviour. Continue reading Guest editing an issue of ‘Essays in Biochemistry’ on the Extracellular Matrix